PHAR 600:  Principles of Drug Design and Development (PD3)
University of Maryland School of Pharmacy

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Module 4 - Principles of Pharmaceutics

Instructor:

R. Gary Hollenbeck, Ph.D.
Associate Professor of Pharmaceutical Sciences
Room 656, Pharmacy Hall
Phone: (410)-706-7670
e-mail: ghollenb@rx.umaryland.edu

Information

Slide shows of in-class presentations are available on-line using the links in the table below. You may also download a handout (Word Document) to use for note-taking during the presentations.

Solutions and Stability Sample Questions are available. 

Answers to these questions are available on line. 

Exam Key Fall 2003

PD3 Module 4 Exam - Hollenbeck Key

Educational Objectives

At the conclusion of the Principles of Pharmaceutics module, the pharmaceutical sciences graduate student will have the ability to identify drug delivery challenges that exist for small and large bioactive molecules in liquid and solid dosage forms, and propose general problem solving strategies for immediate and/or controlled release drug delivery objectives.

Topics

Topic Objectives

at the completion of this module, the student will have the ability to...

Faculty

Dates & times

Design and Performance Issues for Liquid Dosage Forms

Downloadable Handouts 

buffer design handout

stability handout

rheology handout

interfacial phenomena handout

colloids handout

design and prepare a buffer system (including the drug) that achieves a target pH, buffer capacity, ionic strength, and/or osmolarity. 

assess the stability of a drug in solution under specified conditions of pH, temperature, and ionic strength.

determine the order of a degradation process and mathematically describe the concentration vs time profile

predict the shelf-life of a product based on accelerated stability data

describe the types of rheological behavior observed for pharmaceutical systems, and design systems with specific flow characteristics

describe the origin of surface and interfacial tension, identify physical and chemical factors that influence interfacial phenomena, and describe the role that surfactants play in pharmaceutical science

describe the stabilizing mechanisms for colloidal dispersions and identify physical and chemical factors that influence colloid stability

Hollenbeck

 

 

 

 

 

11/7,

12-2

 

 

11/12. 12-2

 

Please contact me if you have questions or if you have difficulty accessing any of the on-line information.

 

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