The Thermo Q-Exactive HF (QE) Quadrupole-Obitrap mass spectrometer is used to identify, quantify, and confirm a variety of large biomolecules, including proteins, peptides, glycans, lipids, metabolites, and drug compounds.
This mass spectrometer is equipped with:
- ESI and HESI probes
- High-resolution, accurate-mass (HR/AM)
- Tandem mass spectrometry: CID and HCD dissociation techniques
- Waters NanoLC system
Experiments using this instrument are for characterization of protein post-translational modifications, targeted structure determination, small molecule and macromolecule molecular weight determination, and metabolite identification/quantification. This HR/AM platform is amenable to untargeted and targeted proteomics, lipidomics, metabolomics, drug discovery, and pharmacokinetic analysis.