Faculty within Patient-Driven Values in Healthcare Evaluation (PAVE) are engaged in a wide range of patient-driven research.

Research conducted within the center aims to elicit elements of value from diverse patients groups, prioritize patient-driven value elements, and test patient-driven value elements in an economic evaluation.

Active Research:

Patient-Informed Values in Cost Effectiveness Analyses

Patient-Informed Values in Cost Effectiveness Analyses

In this three-minute video, Julia Slejko, PhD, assistant professor in the Department of Pharmaceutical Health Services Research and research core lead for Patient-Driven Values in Healthcare Evaluation (PAVE), explains the importance of incorporating the patient's perspective and values into cost effectiveness analyses.

Value Element Assessment among Individuals with Chronic Obstructive Pulmonary Disease (COPD)

The PAVE team is conducting research to examine the elements of value in health care interventions and services that are most important to individuals living with COPD. Researchers will measure the utility and trade-offs in the benefits and risks of key value elements and then incorporate these into an economic evaluation. We will test different methodological approaches for patient-drive value assessment in health care interventions and services for individuals with COPD. This work will be conducted in collaboration with our patient community partners and is supported by PhRMA. To learn more about our research, contact Susan dosReis, PhD, professor and director of PAVE, at sdosreis@rx.umaryland.edu, and Julia Slejko, PhD, assistant professor in the Department of Pharmaceutical Health Services Research, at jslejko@rx.umaryland.edu.

Meeting Presentations:

Click or tap on the meetings listed below to view a complete list of posters, presentations, and workshops delivered at each meeting.

ISPOR 2019 Conference Posters and Presentations

Podium Presentation:
Eliciting Value Elements for a Patient-Driven Value Assessment
Authors: Y. Hong, C. Zhang, J.F. Slejko, S. dosReis

An Analytic Approach to Incorporating Patient Preferences into Value Elements for Economic Evaluation
Authors: dosReis, S., Slejko, J.F., Lakdawalla, D.N., Wilke, R.J.

Identifying COPD Patient-Informed Value Elements in Economic Evaluations: A Systematic Review
Authors: C. Gray, J.F. Slejko

Aligning COPD Outcomes with Patient-Informed Value Element Domains for Use in Economic Evaluations
Authors: J.F. Slejko, C. Gray, Y. Hong, J.D. Rueda, C. Zhang, S. dosReis

Prior Research:

Dr. Joey Mattingly presents his research to attendees at the PAVE kick-off meeting.Engaging an Underserved Patient Community to Inform and Improve Comparative Effectiveness Research for Hepatitis C Treatments

A comprehensive review of the literature on published cost-effectiveness analyses for hepatitis C virus (HCV) treatments revealed that very little had been done to engage patients. Based on our clinical experience, we knew that many HCV patients report psychological and socioeconomic challenges but did not feel that these domains were being reflected in the economic models underpinning cost-effectiveness analyses. This capacity-building grant enabled the formation of a new research collaborative between patients, clinicians, researchers, and the American Liver Foundation. We seek to expand upon this preliminary work by investigating further the elements that are most important to patients in value-based decision making. Through this process, we will inform patient-driven cost-effectiveness analyses.

Patient-Centered Videos: Products generated from this work include:

Acknowledgement: This capacity-building grant was supported by a PCORI Pipeline to Proposal Award 2017-2018 (Principal Investigator: T. Joseph Mattingly II) Specific Project Details: PCORI Link


Mattingly, T.J., Slejko, J.F., Perfetto, E.M., dosReis, S. Putting Our Guard Down: Engaging Multiple Stakeholders to Define Value in Healthcare. Health Affairs Blog. January 2019.

Slejko, J.F., Mattingly, T.J., Mullins, C.D., Perfetto, E.M., dosReis, S. The Future of Patient-Driven Healthcare Evaluation: The Patient-Informed Reference Case. Value Health. 2019; 22(5):545–548.