An agenda for the Computer-Aided Drug Design (CADD) Symposium to be held on Wednesday, May 23, 2018, is provided below for the convenience of symposium attendees.

All presentations and activities will be held at the SMC Campus Center, Room 349, at the University of Maryland, Baltimore (UMB).

Download a printer-friendly version of the agenda here.

TimeActivity
8:00-8:50 a.m. Breakfast and Poster Set-Up
8:50-9:00 a.m. Opening Remarks
Peter Swaan, PhD
Professor of Pharmaceutical Sciences
Associate Dean for Research and Graduate Education
University of Maryland School of Pharmacy
9:00-9:30 a.m. Drug Discovery at UMB (CBT/CADD)
David Weber, PhD
Professor of Biochemistry and Molecular Biology
Director, Center for Biomolecular Therapeutics
University of Maryland School of Medicine

Alexander MacKerell, PhD
Grollman-Glick Professor of Pharmaceutical Sciences
Director, Computer-Aided Drug Design (CADD) Center
University of Maryland School of Pharmacy
9:30-10:00 a.m. Incorporating pH in Structure-based Drug Design
Jana Shen, PhD
Associate Professor of Pharmaceutical Sciences
University of Maryland School of Pharmacy
10:00-10:30 a.m. Structure Prediction and Docking of Therapeutic Antibodies
Jeffrey J. Gray, PhD
Professor, Department of Chemical and Biomolecular Engineering
Johns Hopkins University
10:30-10:45 a.m. Coffee Break
10:45-11:15 a.m. Molecular Dynamics Studies of Antibodies
Sandeep Somani, PhD
Senior Scientist
Janssen Pharmaceuticals
11:15-11:45 a.m. Water Proton NMR for Non-invasive Chemical Analysis and Drug Product Inspection
Bruce Yu, PhD
Professor of Pharmaceutical Sciences
Director, Bio- and Nano-technology Center
University of Maryland School of Pharmacy
11:45 a.m. - 12:15 p.m. Elucidating Protein-Protein Interactions Using Scattering and Molecular Simulations
Joseph Curtis, PhD
Research Chemist
National Institute of Science and Technology
12:15-1:15 p.m. Lunch and Poster Session
1:15-1:20 p.m. Overview of the Department of Pharmaceutical Sciences
Paul Shapiro, PhD
Professor and Chair
Department of Pharmaceutical Sciences
University of Maryland School of Pharmacy
1:20-1:30 p.m. Technology Transfer at UMB
1:30-2:00 p.m. The Formulation of Therapeutic Antibodies for Colonic Delivery
Stephen Hoag, PhD
Professor of Pharmaceutical Sciences
Director, Good Manufacturing Practice (GMP) Facility
University of Maryland School of Pharmacy
2:00-2:30 p.m. Probing Protein Structure In Vivo
Lisa Jones, PhD
Assistant Professor of Pharmaceutical Sciences
University of Maryland School of Pharmacy
2:30-3:00 p.m. Chemometric Processing of Monoclonal Antibody Therapeutic NMR Spectra for Rapid and High Resolution Structural Analysis
Luke Arbogast, PhD
Research Chemist
National Institute of Science and Technology
3:00-3:30 p.m. Coffee Break
3:30-4:00 p.m. Teaching an Old Dog New Tricks: Developing FosA Inhibitors to Potentiate the Antibiotic Fosfomycin
Eric Sundberg, PhD
Professor of Medicine
Co-Director, Basic Science Division
Institute of Human Virology
University of Maryland School of Medicine
4:00-4:30 p.m. Inhibiting DNA Repair through Fragment-Based Methods
Alex Drohot, PhD
Associate Professor of Biochemistry and Molecular Biology
University of Maryland School of Medicine
4:30-5:00 p.m. Drug Design and Discovery: A Small Pharma Perspective
Suresh Singh, PhD
Vice President
HotSpot Therapeutics
5:00-6:30 p.m. Poster Session with Beer, Wine, and Cheese
Note that the posters will be available throughout the day.