MALDI-Mass Spectrometry Imaging of Drug Metabolism

Mark your calendars for MALDI-Mass Spectrometry Imaging of Drug Metabolism, a conference sponsored by the University of Maryland Center of Excellence in Regulatory Science and Innovation and the Food and Drug Administration.

About the Event:

Matrix-assisted laser desorption ionization – mass spectrometry imaging (MALDI-MSI) is an analytical technique that allows for spatial characterization of the molecular content of intact tissues or cell culture via mass spectrometry. This analytical approach has been useful for following drug metabolism and mapping drug distribution, as well as for evaluating local cellular changes or side effects of drug substances. Use of MALDI-MSI as a drug development tool has benefits and challenges but is also amenable to novel drug development systems.

MALDI-Mass Spectrometry Imaging of Drug Metabolism‌ will be held on Tuesday, April 8, 2014 at the University of Maryland School of Pharmacy, located at 20 N. Pine Street in Baltimore, MD. Topics of discussion may include:

  • Using MALDI-MSI to bridge biology and chemistry in drug development
  • Using unique cell-based models to study toxicity
  • Accessibility of MALDI-MSI technology
  • Use of MALDI-MSI for drug distribution studies
  • Use of diverse data sources to aid in the prediction of drug action based upon molecular descriptors

Speaker presentations will be followed by a panel discussion on MALDI-MSI as a drug development tool. Discussion will include current challenges, status of adoption by industry, and potential regulatory impact.

About the Sponsor:

Center of Excellence in Regulatory Science and Innovation The Center of Excellence in Regulatory Science and Innovation (CERSI) focuses on modernizing and improving the ways in which drugs and medical devices are developed and evaluated. It is a collaborative partnership between the Food and Drug Administration (FDA) and the Baltimore and College Park campuses of the University of Maryland.

For More Information:

More information, including registration, agenda, accommodations, and parking and directions, can be found on this website.