An agenda for the UMB-JHU Joint Symposium on Drug Discovery is provided below for the convenience of event attendees.

Scheduled for Wednesday, March 22, 2023, this half-day conference will feature oral presentations chosen from submitted abstracts as well as poster presentations that showcase the robust community of drug discovery researchers in the Baltimore area.

Ample networking opportunities will also be provided during the symposium through lunch and evening cocktails to help foster informal interactions among participants and reinforce foundations for future collaborative efforts between the two institutions.

11:30 a.m. Registration Opens
11:30-1:00 p.m. Networking Lunch and Poster Session
Oral Session I
Translational Research Projects: Short Talks
1:00-1:20 p.m. Introduction to the ICTR UMB/JHU Drug Discovery and Development Program
Paul Shapiro, PhD, professor, pharmaceutical sciences, and associate dean for research and advanced graduate studies (UMB)

Barbara Slusher, PhD, MAS, professor, neurology, director, Johns Hopkins Drug Discovery (JHU)
1:20-1:35 p.m. Using pre-computed conformational ensembles in drug design: a practical example targeting the heterogenous ribonucleoprotein A18
Wenbo Yu, PhD, research assistant professor, pharmaceutical sciences (UMB)
1:35-1:50 p.m. Topical SCD-153, a 4-methyl itaconate prodrug, for the treatment of alopecia areata
Jerry Tsai, MPH, dermatology (JHU)
1:50-2:05 p.m. PROTAC Mediated Degradation of CDK9 for Treatment of Pediatric AML
Alexandria Chan, BS, pharmaceutical sciences (UMB)

2:05-2:20 p.m.
Discovery of microglial-targeted glutaminase inhibitors for the treatment of chronic stress-associated depression
Xiaolei Zhu, MD, PhD, assistant professor, psychiatry (JHU)
2:20-2:35 p.m. Protein-polymer bioconjugate nanoparticles to modulate innate and antigen-specific CD4+ T cell responses
Brianna Scotland, BS, pharmaceutical sciences (UMB)
2:35-2:50 p.m. nSMase2 Inhibition to inhibit late-stage viral assembly
Seung Wan Yoo, PhD, neurology (JHU)
Oral Session 2
UMB/JHU Collaborative Translational Projects: Keynotes
3:10-3:40 p.m. Developing a novel Wnt/╬▓-catenin inhibitor for cancer treatment
Fengtian Xue, PhD, associate professor, pharmaceutical sciences (UMB)
3:40-4:10 p.m. Discovery of a gut-restricted GCPII inhibitor for IBD inflammation and pain
Diane Peters, DMV, PhD, assistant professor, pharmacology and molecular sciences (JHU)
4:10-6:00 p.m. Poster Session and Evening Cocktails