Researchers in the Bio- and Nano-Technology Center (BNTC) are involved in a number of cutting-edge studies aimed at developing enabling technologies to support the translation of basic science findings into medicines for patients.

Dr. Bruce Yu demonstrates how his flow water proton NMR device works.Flow Water Proton NMR as Contact Free Real-Time In-Line PAT for Continuous Biomanufacturing
Funding Source: National Institute for Innovation in Manufacturing Biopharmaceuticals (NIIMBL)
This project develops a contact-free in-line process analytical technology for continuous biomanufacturing.

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Vaccine being injected into arm.Immunomodulatory Biomaterials
This project aims to apply engineering principles to program the immune system. Researchers in the Pearson Lab develop novel immunomodulatory polymers to modulate immune responses with the goal to create anti-inflammatory materials and polymer-based vaccines.

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Blue DNA helices against a black background.Noninvasive Analytics for Biologics Formulation
Funding Source: UM Venture
This project develops noninvasive analytics for protein formulation.




Virus as seen under an electron microscope against a green background.Targeted Drug Delivery
This project aims to develop novel nanomedicines to provide precise delivery of therapeutic payloads (i.e., small molecules, peptides, proteins, and others) to target cell populations to increase therapeutic efficacy while minimizing off-target effects.

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Nanoparticles with very dense PEG coatings (green) are shown penetrating within brain tissue in vivo.Translational Therapeutics Research Group (TTRG) at the University of Maryland School of Medicine
The TTRG is a multidisciplinary team of clinicians, engineers, and cancer biologists actively working together to solve life-limiting treatment challenges in the neuroscience and cancer fields.

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