Agenda

An agenda for the Frontiers in Metals and Medicine to be held on Thursday and Friday, October 24-25, 2024, is provided below for the convenience of the attendees.

All presentations will be held at the University of Maryland School of Pharmacy in Pharmacy Hall, Room N111.

6:00-6:10 p.m., Welcome: Angela Wilks, Fengtian Xue, and Iqbal Hamza
6:10-7:10 p.m., Keynote Speaker: Professor Valeria Culotta, Johns Hopkins University, Bloomberg School of Public Health, “Metals Rock Fungal Pathogens”
Session chair: Iqbal Hamza, University of Maryland School of Medicine

Session Chair: Angela Wilks, University of Maryland School of Pharmacy

9:00-9:25 a.m., Tracy Rouault- “Iron Sulfur Cofactors Play Critical Previously Unsuspected Roles in Viral Replication and Heme Biosynthesis in Mammals" National Institue of Child Health and Human Development (NICHD)
9:25-9:50 a.m., Svetlana Lutsenko- “The Role of Copper Transporters in Cell Differentiation and Morphology” Johns Hopkins University School of Medicine
9:50-10:15 a.m., Joanna Melia- “Aberrant Manganese Homeostasis Disrupts N-glycosylation to Drive Intestinal Inflammation Associated with Crohn’s Disease” Johns Hopkins University School of Medicine
10:15-10:30 a.m., Flash talk selected from poster abstracts

10:30-11:00 a.m., Coffee Break

Session Chair: Daniel Deredge, University of Maryland School of Pharmacy

11:00-11:25 a.m., Caroline Philpott- “Special Delivery: Chaperoning Iron in Mammalian Tissues” National Institute of Diabetes and Digestive and Kidney Disorders (NIDDK)
11:25-11:50 a.m., Emily Weinert- “Exploring the Intersection of O₂ Sensing, c-di-GMP Signaling, and Metal Homeostasis in Bacteria.” Pennsylvania State University, Department of Biochemistry & Molecular Biology
11:50-12:15 p.m., Molly Sutherland-“Heme Binding in Bacterial Cytochrome C Biogenesis" University of Delaware, Department of Biological Sciences
12:15-12:30 p.m., Flash talk selected from poster abstracts

12:30 PM-2:00 p.m., Lunch and Poster Session

Session Chair: Anthony DeMartino, University of Maryland School of Medicine

2:00-2:25 p.m., Mark Gladwin, dean-"Translating Redox Biology to Medicine: Formation and Signaling by an NO-ferroheme Complex Provides a Novel Pathway for Intravascular and Intracellular NO Signaling” University of Maryland School of Medicine
2:25-2:50 p.m., Sarah L.J. Michel, dean-“H₂S Reactivity with Zinc Finger Proteins: A Molecules to Proteins to Cells Approach” University of Maryland School of Pharmacy
2:50-3:15 p.m., Maureen Kane,- “Empowering Metallotheraputic Drug Discovery and Development with Mass Spectrometry-based Approaches” University of Maryland School of Pharmacy, executive director, Mass Spectrometry Center
3:15-3:40 p.m., Paul Buehler- “Animal Models for Preclinical HBOC Down Selection” University of Maryland School of Medicine, Center for Blood Oxygen Transport & Homeostasis
3:40-4:00 p.m., John Phillips- “Heme biosynthesis: Assaying the eight essential steps to produce heme” University of Utah, Center for Iron and Heme Disorders

4:00-4:25 p.m., Coffee Break

Session Chair: Amanda Oglesby, University of Maryland School of Pharmacy

4:25-4:50 p.m., Aaron Smith- “A Ferrous Iron Two-Component System in Pseudomonas aeruginosa” University of Maryland, Baltimore County, Department of Chemistry
4:50-5:15 p.m., Brantley Hall- “BilR is a Gut Microbial Enzyme that Reduces Bilirubin to Urobilinogen” University of Maryland, College Park
5:15-5:30 p,m., Fengtian Xue- “Gallium Complexes as Antipseudomonal Agents by Targeting the Heme Sensing and Utilization Systems” University of Maryland School of Pharmacy
5:30-5:45 p.m., Flash talk selected from the posters
5:45 p.m., Closing Remarks

5:45-7:00 p.m., Wine & Cheese Social + Poster Session