An agenda for the Metallotherapeutics Research Center's first Mid-Atlantic Symposium, "Frontiers in Metals in Medicine," is provided below for the convenience of symposium attendees.
The symposium is scheduled for Friday, Nov. 15, 2019, from 9 a.m. to 5 p.m. at the University of Maryland School of Pharmacy, located at 20 N. Pine Street in Baltimore, Md.
Time | Activity |
---|---|
8:30-9 a.m. | Welcome Breakfast Coffee, pastries, and bagels |
9-9:15 a.m. | Introduction to the Mission and Goals of the Metallotherapeutics Research Center Angela Wilks, PhD Isaac E. Emerson Professor & Program Chair in Chemical and Biological Discovery Department of Pharmaceutical Sciences University of Maryland School of Pharmacy Sarah Michel, PhD Professor and Associate Dean for Graduate Programs Department of Pharmaceutical Sciences University of Maryland School of Pharmacy |
Session I: Identification and Characterization of Metallotherapeutic Targets Session Chair: Susana Mouriño (University of Maryland, Baltimore) | |
9:15-9:40 a.m. | Characterization of the Ferrous Iron Transport Protein FeoC Aaron T. Smith, PhD Assistant Professor Department of Chemistry and Biochemistry University of Maryland, Baltimore County |
9:40-10:05 a.m. | Iron Transport at the Mitochondrial Membrane and at the Host Pathogen Interface of Legionella pneumophila: A Tale of Two Transporters Anirban Banerjee, PhD Investigator National Institute of Child Health and Human Development |
10:05-10:30 a.m. | Metals and ROS: Tales from a Successful Fungal Pathogen Valeria Culotta, PhD Professor Department of Biochemistry and Molecular Biology Johns Hopkins University School of Medicine |
10:30-10:40 a.m. | Flash Talk Selected from Poster Abstracts |
10:40-11 a.m. | Coffee Break |
Session II: Synthesis of Metal Based Inhibitors Session Chair: Iqbal Hamza (University of Maryland, College Park) | |
11-11:25 a.m. | Anti-Virulence by Targeting the Pseudomonas aeruginosa Heme Oxygenase (HemO) Fengtian Xue, PhD Associate Professor Department of Pharmaceutical Sciences University of Maryland School of Pharmacy |
11:25-11:50 a.m. | Brain-Prevalent Metals Influence the Conformational Profile of Alpha-Synuclein Assemblies Heather R. Lucas, PhD Assistant Professor of Chemistry Virginia Commonwealth University |
11:50 a.m. - 12:15 p.m. | Enhancing Fragment-Based Drug Discovery with Metallofragments Seth Cohen, PhD Professor Department of Chemistry and Biochemistry University of California, San Diego |
12:15-12:25 p.m. | Flash Talk Selected from Poster Abstracts |
12:30-2 p.m. | Lunch and Poster Session |
Session III: Metals and Disease Session Chair: Amanda Oglesby-Sherrouse (University of Maryland School of Pharmacy) | |
2-2:25 p.m. | Mischief Managed: Chaperoning Iron in the Cells and Tissues of Mammals Caroline Philpott, MD Section Chief, Genetics and Metabolism Section Liver Diseases Branch National Institute of Diabetes and Digestive and Kidney Diseases |
2:25-2:50 p.m. | New Regulatory Mechanisms Directing Adaptation to Cu Stress in the Opportunistic Pathogen Cryptococcus neoformans Aaron D. Smith, PhD Postdoctoral Fellow Duke University School of Medicine |
2:50-3:15 p.m. | Copper Homeostasis and the Processing of Dietary Fat in Intestine Svetlana Lutsenko, PhD Professor of Physiology Johns Hopkins University School of Medicine |
3:15-3:25 p.m. | Flash Talk Selected from the Posters |
3:25-3:45 p.m. | Coffee Break |
Session IV: Emerging Tools and Technologies in Metallotherapeutics Session Chair: Maureen Kane (University of Maryland School of Pharmacy) | |
3:45-4:10 p.m. | Translational Bioinorganic Chemistry: Applying LC-ICP-MS to Track Iron Nanoparticles in a Clinical Trial Sarah Michel, PhD Professor and Associate Dean for Graduate Programs Department of Pharmaceutical Sciences University of Maryland School of Pharmacy |
4:10-4:35 p.m. | New Tools for Studying Cellular Metal Ion Transport Richard N. Thompson, PhD Associate Professor of Biochemistry and Molecular Biology University of Maryland School of Medicine |
4:35-5 p.m. | Uncovering Targetable Conformers of the Cytoplasmic Heme Binding Protein PhuS from P. aeruginosa Using HDX-MS and In-Silico Ensemble Refinement Daniel Deredge, PhD Assistant Professor University of Maryland School of Pharmacy |
5-6:30 p.m. | Wine and Cheese Social |