The High Throughput Screening (HTS) Facility at the University of Maryland School of Pharmacy maintains state-of-the-art instrumentation to assist researchers in the field of drug discovery with assay design and validation.

Instrumentation:

The HTS Facility hosts state-of-the-art liquid handlers and multi-mode plate readers that can be integrated into screening systems for automation. The two plate readers employ high sensitivities for all common modalities including absorbance, fluorescence, time-resolved fluorescence, fluorescence polarization and luminescence. Liquid handling capabilities allow for volume transfers ranging from 0.1 µL to liters.

Liquid Handling:

  • Biomek FXp-514 dual multichannel span-8
  • Biomek FXp-630 dual multichannel span-8

Microplate Readers:

  • Beckman Coulter Paradigm Detection Platform Multi-Plate Reader
  • MD SpectraMax M5e Multimode Plate Reader
  • BioTek Synergy H1

Plate Storage:

  • Cytomat Microplate Hotels
  • Thermo Cytomat 2C450-LIN ToS Incubator
  • Thermo ALPS-3000 Plate Sealor