Proteomics

The Mass Spectrometry Center's expertise and available applications in proteomics are outlined below.

• Peptide and protein identification of simple and complex protein mixtures
  • Gel bands (e.g., Coomassie blue and silver stained)
  • Immuno-precipitation (IP)
  • Whole-cell, secreted, sub-cellular compartments, tissue digests

• Post-Translational Modifications (PTM)

• Chemically cross linked peptides

• Protein-drug adducts

• de novo peptide sequencing

• Top-down whole protein analysis

• Hydrogen Deuterium Exchange (HDX) for higher structure analysis